• Polymorphic VT VF storms can occur

  2019-04-19

  

  Polymorphic VT/VF storms can occur in patients with severe quinacrine failure, independent of their underlying causes. Recent experimental studies using a pacing-induced heart failure model showed that heart failure facilitates acute shortening of the APD immediately after VF termination [73]. Persi

• Holter ECG monitoring was performed after the

  2019-04-19

  

  Holter ECG monitoring was performed after the patient consumed 180mL of sake (alcohol) each night in both the DDD-R and DDD-CLS modes. The mean HR in the DDD-CLS mode (68bpm) was similar to that (71bpm) in the DDD-R mode, but during sleep, the atrial pacing ratio (43.2%) in DDD-CLS was significantly

• br Disclosures br Acknowledgments br Introduction Long term

  2019-04-19

  

  Disclosures Acknowledgments Introduction Long-term endurance sports have recently been recognized as one of the risk factors for atrial fibrillation (AF) [1–8]; widely accepted risk factors for AF include age, hypertension, diabetes mellitus, structural Metabolism Compound Library disease,

• br Approval statement br Role of the

  2019-04-19

  

  Approval statement Role of the funding source Conflict of interest Acknowledgments Introduction Osteosarcoma (OS) is the most common malignancy of bone, mainly affecting children, adolescents and young adults. According to the American Cancer Society, 750–900 new cases of OS are diagn

• In summary current evidence suggests that bone targeted agen

  2019-04-19

  

  In summary, current evidence suggests that bone-targeted agents reduce morbidity from metastatic disease to bone, and potentially improve quality of life in patients with metastatic breast cancer. As there are costs and potential adverse effects associated with these agents, care should be taken in

• Both breast cancer and MM cause osteolytic

  2019-04-19

  

  Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit

• Introduction Catheter ablation of accessory pathways APs can

  2019-04-19

  

  Introduction Catheter ablation of accessory pathways (APs) can be challenging depending on the location of the AP. Anteroseptal APs are rare but associated with lower success rates and higher incidence of atrioventricular (AV) block [1,2]. Data regarding the electrocardiographic and electrophysiolo

• En ella se muestran los criterios

  2019-04-18

  

  En ella se muestran los criterios sobre los que se acepta negociar en los diálogos de paz en La Habana. Fuera de estas reglas de juego para la negociación, se establecen puntos en común en ella y que según Aira: “Es indiscutible que el ‘Poder’ desempeña un papel fundamental dentro de la negociación”

• Interpretation Haitian children have unacceptable rates of

  2019-04-18

  

  Interpretation Haitian children have unacceptable rates of raised blood lead concentrations, with an unexplained disproportionate elevation in children living in the Centre department. Our findings suggest that routine, widespread screening, detailed investigation into modifiable risk factors, targe

• br Introduction Percutaneous transcatheter device

  2019-04-18

  

  Introduction Percutaneous transcatheter device closure of atrial septal defects (ASD) has become an effective alternative therapy to surgical repair in patients with secundum type ASD. Amplatzer ASD or ventricular septal defect (VSD) occluders were used for the closure of ASDs or VSDs, respective

• SQ 22536 If a structurally normal patient with polymorphic V

  2019-04-18

  

  If a structurally normal patient with polymorphic VT/VF storm has a completely normal baseline ECG, the possible diagnosis includes CPVT and idiopathic VF. CPVT is an inherited disorder of intracellular Ca2+ handling, which can cause polymorphic VT/VF storms [10]. Abnormal SR Ca2+ release from defec

• In addition we evaluated the

  2019-04-18

  

  In addition, we evaluated the left atrium–left ventricle contraction sequence caused by the interatrial conduction delay. When we performed AV sequential pacing using the nominal AV delay setting, left atrial contractions were significantly delayed and were almost simultaneous with the left ventricu

• In an effort to determine whether the primary

  2019-04-18

  

  In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi

• Atrial fibrillation is the most common atrial arrhythmia stu

  2019-04-18

  

  Atrial fibrillation is the most common atrial arrhythmia studied in BrS [3–14]. The prevalence of AF has been reported to be higher in patients with BrS than in the general Ubenimex of the same age [15,16]. Earlier studies reported an approximately 10–50% prevalence of spontaneous, clinical AF in pa

• Human ether a go go related gene HERG

  2019-04-18

  

  Human-ether-a-go-go-related gene (HERG) encodes the α-subunit of rapidly-activating delayed-rectifier potassium Epoxomicin that generate IKr. This outward potassium current is elicited during the plateau phase of action potentials and is required for repolarization [4]. After being translated in th

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