• To ascertain separation of the distinct enzymatic activities

  2019-10-18

  

  To ascertain separation of the distinct enzymatic activities found in this protein preparation following separation on the HAP column, a rigorous quantitative analysis was conducted on the nickel–agarose elution and HAP FT pools of protein. For these analyses, each pool of protein was dialyzed in th

• Interest in DGKs increased as it became

  2019-10-18

  

  Interest in DGKs increased as it became clear that not only are they important for lipid homeostasis, they serve to modulate the relative levels of diacylglycerol (DAG) and phosphatidic BB-94 (PtdOH) that play critical roles in a variety of signaling pathways (Eichmann and Lass, 2015; Liu et al., 2

• Our observation that FAK is downregulated in vascular smooth

  2019-10-18

  

  Our observation that FAK is downregulated in vascular smooth muscle L-161,982 on fibrillar collagen confirms observations reported for other cell types [14]. However, unlike the results reported previously [14], our work suggests that matrix rigidity per se does not determine FAK downregulation. Thi

• LTD and LTC cause contraction in

  2019-10-18

  

  LTD4 and LTC4 cause contraction in the rat stomach and these contractions are sensitive to CysLT1 receptor antagonists (Goldenberg and Subers, 1983, Miura et al., 1992, Miyata et al., 1995). However, effects of other leukotrienes in the gastric contraction and inhibitory effects of potent, selective

• While several C terminal peptides have

  2019-10-18

  

  While several C-terminal peptides have been reported to have modest (astressin) or substantial (astressin2-B, antisauvagine-30) subtype selectivity for the CRF2 receptor (), [125I]YP20 is the first reported small analog of the C-terminus of CRF exhibiting subtype selectivity for the CRF1 receptor vs

• Stressful life events are modulators of mood and

  2019-10-18

  

  Stressful life events are modulators of mood and can trigger a variety of destructive behavior, including drug abuse and relapse in addicts (Association, 2013; Chen et al., 2012; Sinha, 2009). Likewise, drug-associated stimuli evoke a negative affective state in abstinent drug users. Compelling evid

• Distribution of DGTS in basidiomycete fungi has been demonst

  2019-10-18

  

  Distribution of DGTS in basidiomycete fungi has been demonstrated to be heterogeneous. In certain fungal taxons, such as Agaricales, Polyporales and Russulales, there are species that synthesize and species that do not synthesize DGTS that belong to the same order or even family (Dembitsky, 1996, Va

• To determine the time course of ZD P

  2019-10-18

  

  To determine the time course of ZD2767P+CPG2 DNA–DNA interstrand cross-link formation, HT29 and LS174T colorectal tumour phosphocreatine kinase were exposed to the drug for 10, 30 or 60 min. The levels of DNA interstrand cross-links in HT29 or LS174T cells did not increase with exposure time, sugge

• It should be noted that the long

  2019-10-18

  

  It should be noted that the long-lifetime binding-responsive luminescence of ARC-1528 and ARC-1530 becomes evident only upon illumination with radiation at near-UV range where the excitation of ATB or ASB moiety is possible. At higher wavelength range (visible light), the fluorophore (5-TAMRA) can b

• br Introduction Cell transplantation therapies

  2019-10-18

  

  Introduction Cell transplantation therapies using embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC)-derived retinal tissue (ESC/iPSC retina) or TDZD-8 have emerged as therapeutic options for retinal degeneration following recent breakthroughs. A number of groups have shown that

• 5046 The aim of this paper is

  2019-10-18

  

  The aim of this paper is to study the long-term socioeconomic impacts of local heat entrepreneurship from 2000 to 2016. The analysis focuses on impacts of the biomass-based district heat production on employment and income in a small peripheral community, called Eno, located in North Karelia, Finlan

• br The classical ubiquitination pathway Ubiquitination is an

  2019-10-17

  

  The classical ubiquitination pathway Ubiquitination is an enzymatic process that involves the addition of an ubiquitin protein to a substrate that usually becomes inactivated followed by degradation in the proteasome; however, several other functions have also been described. For the discovery of

• mibefradil One possible explanation for differences in the b

  2019-10-17

  

  One possible explanation for differences in the binding ability of monomeric versus dimeric forms of DDR2 ECD to collagen could be that the monomeric form only binds to the primary GVMGFO site, whereas dimeric (and oligomeric) DDR2 ECD binds to additional sites on the collagen triple-helical molecul

• There are numerous resources clinicians may

  2019-10-17

  

  There are numerous resources clinicians may use to gather information on the strength of evidence related to pharmacogenetic-based dosing and treatment decisions, as well as specific dosing guidelines, some of which are summarized in this review. These include resources from CPIC, which provides pee

• In general up to date no study has considered thermodynamic

  2019-10-17

  

  In general, up to date, no study has considered thermodynamic modeling to estimate the N6-Methyl-ATP of SO2 by different DESs. Since experimental measurements are time consuming and expensive, general and accurate theoretical models are vital to estimate SO2 solubilities in different DESs over wide

15121 records 909/1009 page Previous Next First page 上5页 906907908909910 下5页 Last page