• br Conclusion br Introduction Multiple myeloma

  2019-06-28

  

  Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not

• Although the CHADS score is useful for evaluating the risk

  2019-06-28

  

  Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of 0 or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so

• In this case report we

  2019-06-28

  

  In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation

• The main inherited arrhythmogenic causes of

  2019-06-28

  

  The main inherited arrhythmogenic causes of SCD in the young are summarized in Fig. 1. These arrhythmogenic disorders include familial long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), Brugada syndrome (BrS), idiopathic ventricular fibrillation, early repolarizat

• In silico prediction software SIFT PolyPhen CADD and other

  2019-06-28

  

  In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com

• Two other groups subsequently published further

  2019-06-27

  

  Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant a

• ICE was introduced as a real time imaging technique to

  2019-06-27

  

  ICE was introduced as a real-time imaging technique to assist catheter ablation procedures. Chu et al. performed an ICE-guided catheter ablation in 9 dogs. They concluded that ICE can accurately guide catheter ablation directed at anatomic landmarks. They also used ICE to confirm the endocardial con

• Close inspection of the tumor matrix on

  2019-06-27

  

  Close inspection of the tumor matrix on the initial and subsequent 5 month radiographs (Fig. 7), shows an atypical appearance for osteoid matrix that KC7F2 weight may more closely resemble chondroid matrix. The matrix appears to display a linear dense lace-like pattern (Fig. 8). Of the only two oth

• Introduction Leukaemias lymphomas and multiple myeloma can b

  2019-06-27

  

  Introduction Leukaemias, lymphomas and multiple myeloma can be the dreadful sequelae of viral infections. RNA oncogenic viruses, which are also known as retroviruses, were initially known to cause lymphoproliferative disorders only in animals, but have also been reported to demonstrate their transf

• The indications for epicardial mapping are institutionally v

  2019-06-27

  

  The indications for epicardial mapping are institutionally variable but typically performed after a failed endocardial approach or if the etiology of cardiomyopathy suggests a high likelihood of epicardial scar (Fig. 9). Studies of patients with NICM that underwent combined epicardial–endocardial ap

• The electrocardiogram showed narrow QRS complex regular tach

  2019-06-27

  

  The electrocardiogram showed narrow QRS complex regular tachycardia, which was terminated by rapid injection of adenosine triphosphate. During the tachycardia, the P wave was not identifiable and was likely hidden completely in the QRS complex (Fig. 1). As the patient desired complete cure of the ta

• The arrhythmia free rate was at

  2019-06-27

  

  The arrhythmia-free rate was 67%–91% at 1-year after multiple ablations depending on HF and LVEF status, although repeat ablations were required for more than half of the patients. One of the mechanisms responsible for tachyarrhythmia recurrences was conduction recovery in the PVs or linear lesions.

• A year old man was

  2019-06-27

  

  A 36-year-old man was hospitalized following a first syncope attack while awake at night. No history of sudden death was reported in his family. On arrival, his consciousness was clear and his vital signs were stable. An electrocardiogram (ECG) showed sinus rhythm with ST-segment elevations and J wa

• br Conclusion Accumulating clinical data suggest the

  2019-06-27

  

  Conclusion Accumulating clinical data suggest the presence of a genetic component in the pathogenesis of AF. In addition to the gene mutations identified in familial AF, the candidate gene approach and GWAS identified genetic risks in the non-familial form of AF. In multiple Western populations,

• The findings revealed that TCZ women of years of

  2019-06-27

  

  The findings revealed that TCZ women of 18–29 years of age had knowledge about the nature of Pap smear as compared to other categories, and they also knew that if cervical cancer was detected early, medication and other early forms of interventions could be initiated to deal with the problem before

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