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Premature deaths of women have profound effects on families
2019-06-18

Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea
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The Zika virus epidemic is spreading
2019-06-18

The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil
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A Framework Convention on Global
2019-06-18

A Framework Convention on Global Health (FCGH)—supported by civil society and global leaders—should become the centrepiece of this endeavour (). It would reform global governance for health to enhance accountability, transparency, and civil society participation and protect the right to health in tr
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Y 134 Cancer stem cells are capable of differentiation and s
2019-06-18

Cancer stem Y 134 are capable of differentiation and self-renewal. In 1994, CSCs were described for the first time. Hematological malignance is the best evidence to support the existence CSCs. TPC (tumor Propagating cell) is the other phrase that has been used for cancer stem cells. CSCs presents a
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br Reimbursement system The current reimbursement regulation
2019-06-18

Reimbursement system The current reimbursement regulations are in need of an update [26,27]. In 2008, the Centers for Medicare and Medicaid Services in the USA approved a revised set of codes developed in collaboration with HRS, the American College of Cardiology, and the American Medical Associa
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The strengths of this definition
2019-06-18

The strengths of this definition are its simplicity and its usefulness in translating existing data into daily practice. The shortcomings of this definition include the lack of uniform criteria to suggest an impending fracture as well as the variable definitions of spinal cord nor-NOHA acetate manuf
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Performing an ajmaline test in
2019-06-18

Performing an ajmaline test in children is problematic for 2 reasons. First, the test is apparently less sensitive in children than in adults. In fact, in 1 study, a repeat ajmaline challenge performed after puberty unmasked BrS in 23% of relatives with a previously negative drug test performed duri
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buy Bay 11-7085 En ese encuentro de intereses entre los dist
2019-06-18

En ese encuentro de intereses entre los distintos grupos, bien sea por dominar el territorio, o por imponer la fuerza, o bien por controlar el negocio del narcotráfico, la población queda expuesta y vulnerable. Los ataques entre unos y otros tienen serias repercusiones sobre los poblados “las accion
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In another study Lopez and associates found that
2019-06-17

In another study Lopez and associates found that patients with chronic heart failure receiving torsemide, a loop diuretic that inhibits the enzyme involved in the myocardial extracellular generation of collagen type I molecules (i.e., procollagen type I carboxy-terminal proteinase or PCP), had reduc
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The canonical or catenin dependent Wnt
2019-06-17

The canonical, or β-catenin dependent, Wnt signaling pathway is critical for the regulation of osteoblast proliferation and survival [95]. Soluble inhibitors of the canonical Wnt pathway such as Dickkopf (DKK1), produced by OBL, and sclerostin, from osteocytes, play important roles in the regulation
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The ability of tumors to progress to
2019-06-17

The ability of tumors to progress to more malignant phenotypes depends on tumor microenvironment. Blood capillaries, made up of endothelial cells, are usually static under physiological conditions but are induced to proliferate by direct exposure to angiogenic factors, for instance, vascular endothe
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br Conflict of interest br Acknowledgment br Introduction Th
2019-06-17

Conflict of interest Acknowledgment Introduction The majority of clot embolisms associated with atrial fibrillation (AF) are from the left atrial appendage (LAA). Before cardioversion or catheter ablation, clot formation needs to be ruled out traditionally using transesophageal echocardiogr
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In their analysis the investigators did not include common c
2019-06-17

In their analysis, the investigators did not include common causes of CKD in sub-Saharan Africa other than HIV, diabetes, and hypertension—notable omissions were chronic glomerulonephritis and use of herbal or traditional treatments. Also, communicable diseases might contribute substantially to CKD
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The combination therapy was exceedingly well tolerated
2019-06-17

The combination therapy was exceedingly well tolerated without any side effects to either drug. Remarkably, despite an advanced PV-stage the JAK2V617F allele burden was rapidly lowered from 90% mutated CCCP at referral to 59% at 6 months, 28% at 10 months and 12% at 16 months of therapy (Fig. 2).
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More recently Brugada et al used flecainide
2019-06-17

More recently, Brugada et al. [131]. used flecainide to identify the full extent of low-voltage electrogram activity in the anterior RV and RVOT and targeted this region for RFA. In all 14 BrS patients, RFA eliminated abnormal bipolar electrograms, normalized ST-segment elevation on right precordial
 
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