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(S)-Crizotinib Based on the methodology used in previous stu
2019-06-12
Based on the methodology used in previous studies, the EGM source for the Wavelet algorithm has been nominally programmed as the Can-RV coil EGM [13]. As the nominal EGM source includes the generator, myopotentials induced due to body motion or other muscle activity are likely to influence the arrhy
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Introduction Benign tumours of the bone
2019-06-12
Introduction Benign tumours of the bone consist of a wide variety of different neoplasms. These tumours vary in terms of incidence, clinical presentation and require a diverse array of therapeutic options. The incidence of benign bone tumours is debated due to their often asymptomatic presentation
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Las formas transmisibles no del saber o
2019-06-12
“Las formas transmisibles, no del saber o de la sabiduría de un hombre, sino sobre todo su vida vivida —y esa es la materia con que se hacen historias— sólo son adquiridas al morir”, afirma Walter Benjamin. La muerte atraviesa toda la Historia verdadera: como motivo, como temor, como asombro o recue
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Houve uma tentativa por aglutinar as fra es
2019-06-11
Houve uma tentativa por aglutinar as frações mais radicais da esquerda em torno da Alianza Revolucionaria de Izquierda (ari), tendo em vista as eleições presidenciais de 1980. No entanto, esta aliança só durou três meses e foi rompida por diferenças mesquinhas entre as dirigências políticas, o que g
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Although a well experienced group reported a very
2019-06-11
Although a well experienced group reported a very high success rate of 80% after catheter ablation even in patients with congestive heart failure [40], the evidence described above suggests that catheter ablation alone is not sufficient to treat AF in patients with hemodynamic deterioration. This in
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Fig shows different PVCs observed before
2019-06-11
Fig. 4 shows 2 different PVCs observed before (PVC 1) and after the application of radiofrequency induced pluripotent stem cells (PVC 2) in patient 17. After ablation of PVC 1, a different PVC (PVC 2) with a slightly different QRS morphology from that of PVC 1 was observed. Fig. 5 shows the activat
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Complete surgical resection of the tumor at
2019-06-11
Complete surgical resection of the tumor at the time of diagnosis is essential towards effective management of PPB. Unfortunately, a large cohort of patients present with an advance stage of disease where the tumor has grown to such an extent to invade surrounding vital structures, hindering the com
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In patients who develop bone
2019-06-11
In patients who develop bone metastases, these are commonly diagnosed at the time of their initial work up for their metastatic disease (∼80%) [7], although others can develop skeletal metastases at any time during the disease course. The consequences of bone metastases include pain (∼80%) [3,6,8] a
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br In Sanguinetti et al and Barhanin et al
2019-06-11
In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs
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These results have to be interpreted with respect to present
2019-06-11
These results have to be interpreted with respect to present trends in age at childbearing. Worldwide, adolescent fertility rates fell from 71 to 52 per thousand women aged 15–19 years between the 1970s and the 2000s. This AS-1404 was seen in all regions, with the possible exception of Latin Americ
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HIV counselling and testing is the essential first step
2019-06-11
HIV counselling and testing is the essential first step to accessing HIV care services and is also recognised as an HIV prevention strategy because knowledge of HIV status reduces risky sexual behaviours. A reduction in the number of sexual partners has been reported, but not a significant increase
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En correspondencia con ese posicionamiento cr tico frente a
2019-06-11
En correspondencia con ese posicionamiento crítico frente endothelin receptor antagonist la propuesta de cambio social de sus respectivos gobiernos, los movimientos sociales tienen entre sus principales objetivos la autonomía material y simbólica, considerada una de las características comunes en el
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A year old male with
2019-06-11
A 52-year-old male with known dextrocardia and CCTGA presented with a 2-month history of recurrent presyncope and effort intolerance. His examination revealed a resting pulse rate of 52beats/min (bpm) and a blood pressure of 130/80mmHg. The apex beat and heart sounds were appreciated on the right si
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br Possible reasons for the divergent
2019-06-11
Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site
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Introduction The assessment of hormonal receptor HR and huma
2019-06-11
Introduction The assessment of hormonal receptor (HR) and human epidermal growth factor receptor-2 (HER2) status by immunohistochemistry (IHC) groups breast cancer into three major subtypes: 1) luminal-like subtype (HR positive/HER2 negative); 2) HER2 subtype (HER2 positive and HR negative/positive
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